DNF-10® is one of five ingredients in Ozenica's Trimfexa® blend. See the full blend and the other four ingredients by clicking below.
Lose the fat. Keep the muscle. That's the difference.
DNF-10®: Fat Loss With Lean Muscle Preservation
DNF-10® is a patented yeast-derived peptide (hydrolyzed Saccharomyces cerevisiae) clinically studied for its ability to support fat loss while preserving lean muscle mass. It is one of the very few natural supplement ingredients with human clinical data — including CT imaging — demonstrating body composition changes, not just weight changes. This distinction matters: most weight loss supplements measure success in pounds. DNF-10® has been studied for what kind of weight is lost — specifically showing support for fat reduction while lean muscle is maintained.
When most people lose weight — through calorie restriction, exercise, or medication — a meaningful portion of what they lose is lean muscle, not just fat. Less muscle means a slower metabolism, faster weight regain, and less strength over time — especially relevant for adults 40+ where muscle loss is already an age-related concern. DNF-10® was selected for the Trimfexa® blend specifically because of this body composition research.
DNF-10® in Ozenica®
Specification
Ingredient form
DNF-10® (patented hydrolyzed Saccharomyces cerevisiae peptide)
Dose per 2-capsule daily serving
500mg
Research basis
Human clinical trials including CT imaging for body composition measurement
Primary benefit studied
Supports fat loss while preserving lean body mass
Stimulant-free
Yes
Frequently Asked Questions
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Most weight loss ingredients focus exclusively on appetite suppression or thermogenesis. DNF-10® is specifically studied for body composition — the ratio of fat lost to muscle preserved. This is a meaningfully different and more complete approach to weight management.
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No. DNF-10® is a yeast-derived peptide with no stimulant properties. It does not contain caffeine, synephrine, or any compound that affects heart rate or energy levels artificially.
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Based on clinical research timelines, body composition changes are typically measurable around weeks 4–8 of consistent use, combined with a balanced diet and regular activity.
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DNF-10® is a yeast-derived peptide that has been studied for supporting fat loss while helping preserve lean muscle. In human clinical research, the weight lost was shown to come from fat rather than muscle, confirmed by CT imaging. This is part of why DNF-10® is of interest to people concerned about the muscle loss often associated with rapid weight loss or prescription GLP-1 medications.